Episode 1:

[caption id="attachment_4249" align="alignleft" width="180" caption="Supernatural Season 6 Episode 1"][/caption]Supernatural Season 6 episode 1 will premiere on September 24, 2010 and got a title of "Exile on Main Street." It continues with where the story stop when the so called "apocalypse" just ended when Lucifer's souls was thrown to the cage that will hold him for sometime. However, it seems that this does not stop the book for the Winchester brothers but opens another book when Sam is shown after the last scene of the season 5 finale.The exclusive video below shows the possible premiere episode shown during the ComicCon 2010 where Crowley is informing Bobby that he is serious with getting his soul for the wish that he have made during the previous episode. You just can't change any demon at all. I am wondering right now if how's Dean Winchester right now and if he really have moved on after the Sam incident. Later you can return here to watch Supernatural season 6 episode 1 online right after its air date on the 24th of September Friday at 9pm E.T.